Immunology

Contact

Address
CENTRO DE INVESTIGACIÓNS BIOMÉDICAS (CINBIO)
Campus Universitario s/n
36310 Vigo
Phone
986 130 141
Website
http://inmunologia.webs.uvigo.es/

Research areas

Research lines
Nanomedicine: potential application of nanostructures in the biomedical field:
-Standarization of methods to check biocompatibility, toxicity and immunogenicity of nanoparticles.
-Biosensors using antibodies and nanostructures.
Tuberculosis.
-Design of an efficient vaccine using nanomaterials for M. tuberculosis.
-Massive transcriptomic in patients and their contacts (infected and non-infected)
-Immune profile of response to M. tuberculosis antigens.
Aquaculture. Design of immunological techniques to detect the presence of different marine organisms and toxins.
Vaccines. Immune response to nanovaccines using different routes of administration (intranasal or intramuscular) on animals models.
Immunotherapy: fully human monoclonal antibodies directed to human cells that could be useful in human therapy.
-Anti-CD69.
-Anti-Class II MHC
-Several directed to human B cells and human monocytes.
Keywords
nanotechnology, nanotoxicology, vaccines, tuberculosis, monoclonal antibodies, massive transcriptomic, biocomputing, autoimmunity, immunotherapy, immune response, Western blot, flow citometry, ELISA, dot blot, phagocytosis, immunodetection, chromatography, molecular biology, cancer, biosensor, immunohistochemistry, animal models (pre-clinical assays)

Technological offer

Services offered
Basic, clinical and applied immunology.
Vaccines.
Development of monoclonal antibodies: human therapy/cell identification.
Nanotechnology: toxicity and immunogenity of nanomaterials.
Cell culture (tumoral and primary cultures).
Molecular biology techniques: PCR, RT-PCER, sequencing, massive transcriptomics.
Phagocytosis studies
Cytotoxicity assays (MTT, LDH, Excelligence...)
Endotoxin detection in different samples
Handling of animals (rat, mouse): study of the immune response for the development of effective vaccines.
ELISA: quantification of cytokines, antibodies and other molecules.
Western blot, dot blot.
Biosensors: electrochemical / lateral flow.
Bacterial cultures.
Flow cytometry, confocal microscopy.
SEM and TEM microscopy.
Histology.
Searching for immunoregulatory substances.
Experimental models of autoimmunity.
Mathematical models and Biocomputing.

Group members

Biología celular
Investigador/a Principal
Inmunología
Coordinador/a
Área externa
Colaborador/a
Área externa
Colaborador/a
Inmunología
Miembro
Área externa
Colaborador/a
Inmunología
Miembro
Inmunología
Personal Apoio
Área externa
Colaborador/a
Área externa
Colaborador/a
Desconocida
Miembro
Inmunología
Miembro
Inmunología
Colaborador/a
Inmunología
Miembro
Inmunología
Miembro
Inmunología
Miembro

Research results